Fit for Health aimed to sustainably enhance the participation of European small or medium-sized enterprises (SMEs) in Calls for the FP7 Health Theme. Focusing on research-intensive, high technology SMEs, the project offered targeted support measures, covering the entire innovation pipeline of the Health sector. Key assets of Fit for Health were highly qualified consultancy, hands-on trainings, effective SME-academia matchmaking and guidance to strategic use of FP7 by SMEs and clusters. Particular attention was  given to SMEs in enlarged Europe, Acceding and Candidate countries. SMEs and researchers were supported during all phases of FP7-projects, including consortium building, proposal writing, grant negotiation, project management and efficient valorisation of project results. Cooperation between SMEs and academia was strongly encouraged by dedicated services and tools. A well-established, highly visible database and a sophisticated matchmaking-tool, already proven in preceding initiatives, suported the formation of competitive project consortia. PThe efficiently managed network was also optimally connected to other key support networks for SMEs.